For younger kids, mine used to like Scrambled States of America. We don't play it much anymore though. For those anatomy lovers... we have an AWESOME game called Skeletons in the closet. This game is so fun, so easy, and doesn't take forever to play. While we LOVE the way things work, it takes much longer to play than this one. Kids learn the names of bones (basic bones, not too detailed) or there is a simpler version of play also. They have to build a skeleton by collecting bones and cartons of milk and what not.

http://www.amazon.com/Skeletons-in-the-Closet-Game/dp/B0008JIL9U