I find that my feelings of being defective with regard to brain or body (and not wanting to be "medicating" myself) can sometimes be alleviated by taking a biological perspective as in, not all bodies work exactly the same, not all bodies even work well, each individual is different, etc. And from there, to take the view of helping your body work better - If you could greatly improve your health by ingesting a chemical that your thyroid doesn't make anymore, wouldn't that be a great idea? If your brain doesn't make enough of the chemicals you need to be on an even keel psychologically, wouldn't it be great if there were a medicine you could take to help your brain out? That sort of thing. I find this helpful, but I expect it won't work for everyone. And I keep thinking of other examples, but I'm sure you get the idea!