I love Jerry from Boston Legal. Christian Clemenson has done a great job with the character. That having been said, I think Jerry's about as representative of the average person with Asperger's as Bethany is of people with dwarfism, or Denny Crane is of the average 70-something attorney.
In general, I tend to shy away from shows with designated Aspies. One of the things I love about Bones is that nobody has a diagnosis. They're all just geeky. That having been said, I'd throw Zack Addy under the bus...well, except maybe the cannibalism thing.