Agree with jack'smom, especially if you have schools like Stanford or Duke on her list. Unless she has some really spectacular extracurricular or other hook, she probably ought to be taking calc & physics. Are there any local colleges where she could volunteer to help with research in the summer in the other areas she is interested in (like zoology?). My D is taking the top science track at her school (no APs offered, but honors bio, honors chem, and honors physics). The only other science course she is planning on is an anatomy course her senior year (in addition to physics). She is very interested in epidemiology and vaccine development, so is looking for research opportunities in those areas over the summers.