Gifted Issues Discussion homepage Forums Twice Exceptional Treating children with Autism using leucovorin?

For forum members who may have 2e children on the autism spectrum, have you seen the news coverage regarding treating children with autism, using leucovorin...?

CBS Evening News
"Parents say off-label drug helped son with autism speak"

h t t p s : / / w w w . y o u t u b e . c o m / w a t c h ? v = Q T 4 E 2 d P T b k c
video length 3:41
video posted Feb 17, 2025

Related weblinks -
1) Dr. Richard E. Frye, Child Behavioral Child Neurologist - https://drfryemdphd.com/
2) https://www.autismdiscovery.org/index.php/home-adtf

Folinic acid is an active metabolite of folate, which is essential for methylation. DNA methylation & demethylation is central to control of all cellular processes, so it’s quite conceivable that Leucovorin would benefit some children on the autism spectrum. I’m not an expert in this field, but in non excessive doses, under appropriate clinical supervision, trial by therapy would seem worthwhile, although it is unlikely to be the panacea for every child on the autism spectrum.