I'm not sure a common and expected effect like initial drowsiness would even be on the report. I would assume the report would be about long-term side effects that would prevent a person from continuing on a medication--not just the first couple weeks.

FWIW both my kids take guanfacine and a stimulent. For my daughter, the stimulent is very effective, but gave her a lot of anxiety in higher doses, so we went with a lot dose + guanfacine. My son just didn't get much help with stimulents, but the guanfacine was noticibly useful to him.

We have not tried genetic testing. Our prescribing specialist didn't think it was reliable enough to bother with.