That is pretty fascinating.

I think I remember that supplementing GABA isn't effective, anyhow, because it doesn't cross blood/brain barrier?

How do they measure "GABA activity in the brain?"

blackcat--my understanding is that executive dysfunction is a fairly pronounced piece of the ASD pie, so yeah. I'm not sure I have this totally right, but I think it's something like when ASD kids are also diagnosed with ADHD, it's not so much that they are distinct disorders (for the ASD person), but that the ADHD diagnosis is useful for understanding the EF part of autism, in people for whom that is a big issue.

A little OT: but the drug gabapentin was originally thought to do something to GABA, but I think *they* changed their minds about that. It is still used a lot for many different conditions, though.