That is terribly sad. I've done evals on kids who experimented with much less deadly substances and seen a similar swiss cheese brain effect. Protracted marijuana use (which many of my students don't consider to be using drugs) often results in what I think of as the shards of a broken mirror--here and there you see flashes of the brilliance that used to be, but the individual can no longer put it together to make a complete image.

...pronounced like the long vowel and first letter of the alphabet...