I have to chime in here, my son has an autoimmune disorder (which began as an autoimmune response to strep-- strep antibodies cross the blood brain barrier and attack his brain) it is called PANDAS and it seems that most of the kids who have this area also gifted, though there is little evidence of giftedness in our house lately.

I do feel that, from what I read about the common difficulties of 2E kids, autoimmunity plays a huge rule, but I have no scientific basis for this really.