I think it depends - if it's just that a friend doesn't have a way to connect to one thing I might talk about, and can't help with problems in that area, that's fine. This is why one should have more than one friend ;-) But if a close friend were unwilling even to listen if I was seriously distressed about something in that area, that'd be a problem. I don't expect my every remark to be responded to, but I wouldn't like to feel there were large no-go areas in discussion with a close friend.
A complication is that in a friendship that's carried on in writing, maybe it isn't always clear which things need responses, either. If that's a factor here, maybe there might be some mileage in trying to ask for what you need more clearly - if you want input on something in particular, say so, by asking a specific question ("what would you do in my place?") or explicitly saying so ("I'd really value hearing your point of view on this" or "Hugs welcomed!" or whatever.)
