Aside from the trip itself, something I have found helpful is preparing for 'jet lag' with kids. Once, taking a U.S. to singapore trip, I worked over a few week prior to the trip on moving DSs bedtime, just a little - maybe half an hour to an hour a night (this only works if you can fit it in with school of course). It really helped when we got there - did brilliantly. Unfortunately, I also had a 3month baby at the time (with no concept of when to sleep of course) - the jet lag for me was a nightmare!
