Can you go back to the pharmacy and trade your old bottle of antibiotic for a new one with sweetener mixed in?
Failing that and if he's already decided he hates all medicine, regardless of flavor:
Umm. This approach works with my cats (if you think it's hard getting a young child to take medicine, try a cat). I mix the medicine into something they really, really like. Pureed-chicken baby food is always a winner. Yum! A treat!
Scaling this approach to a child, you could try mixing the antibiotic into something that will hide the bitter flavor of the medicine, such as soupy ice cream. You may have to do a little trial and error to find an amount of ice cream (or whatever) that will hide the flavor, yet not be too much to eat in a single go.
Val