My (MG and aspie) DD got really distressed by the first HS book she read, I think it was Monstrous Microbes. She finished it in the end but hasn't read any more and it's definitely fed her germ phobia and excessive hand washing tendencies.... But that's more about the type of kid she is than the books, this is a kid who used to want to be a DR so she could cut up dead bodies at Uni (charming I know) and now falls apart at the mere suggestion her sister might need a blood test, and is icked out by all things sticky and messy. Her sensory seeking younger child is morphing into extreme sensory avoiding tween. She was on that path already but the Monstrous Microbes did not help.