We homeschooled while both parents worked, as well.
I was working as a pharmacology researcher, and DH as a senior engineer at a high tech company.
I worked part time and in the evenings, and my DH was able to work flexibly from home several afternoons each week. I also had the ability to take DD to work with me occasionally, where she could work with a laptop computer, in a workbook, or just read (what she did most often). She also used to follow me around and ask a lot of questions as long as I wasn't using radiation or serious biological or chemical hazards.
We were able to successfully balance this way for almost a decade.
It isn't easy, though-- and the down side is that doing things the way we did (with no respite or additional caregivers) is exhausting with any child, and with a PG highly intense child it is even moreso.
I'll also say that as DD became a middle school student, it became much harder, and when she entered 8th grade was when I had to admit that we needed a full-time at home parent to continue. I couldn't be in two places at once, and I couldn't be doing my job well and be a good homeschooling parent for a PG 10 yo as well as a successful advocate for her and spouse to my husband.
With a regular daily (non-parent) caregiver, it might well have been different.
