We had this done and it showed that the methylphendiate drugs were in that "yellow" category. She had tried those and they did help, but not as much as one would expect. She also had a lot of moodiness. Interestingly almost all of the antidepressants came out on the "red" list, with the warning that they had an increased risk of side effects. So I'm glad we never went down the road of trying antidepressants that are normally prescribed for kids, and risked watching her get moodier and moodier rather than improving. I think the gene testing may be useful for ADHD meds if you have tried various meds and had nasty side effects or just couldn't find anything that worked. It can lead a person in the right direction, but it's not foolproof. Guanfacine was on her "yellow" list and she has tried it, and I never felt like it did that much. I read somewhere that it is helpful in kids but not adolescents/adults.