The genetic test for medication efficacy has been pretty accurate for us. We actually tried the meds first and then got the results back, so it basically explained what we were seeing. It will depend on what your variances actually were, but here’s what happened for us. DD is resistant to methylphenidate based stimulants through two pathways. For her, when we tried long acting methylphenidate, which should have an onset within an hour and an effect for about 8-9 hours, we saw that it took 3-4 hrs for onset. Duration from time of ingestion was about the same, meaning we only saw about 3.5-4 hrs of effect. Increasing the dose caused emotional lability but didn’t increase the duration of effect.
HTH. Happy to answer any questions.
