Well, I'm certainly not selling the stuff. Nor am I wildly recommending it, a la "You all should go out and buy this ASAP."

In this case, I feel encouraged by what appears to be hundreds of years of folk use. It's not a new remedy by any means.

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Okay, so if you assume that "molecule A" is the active ingredient, and you standardize on that basis, what happens if you're... er.... well, wrong? What if it is actually molecule H that has the activity that is desirable?

Right. There does appear to be some understanding of this with Rhodiola, but I'll freely admit that I'm in no position to judge if it's correct.

I guess I'll just reiterate that this herb appears to have had far more scrutiny than most and to have come out looking better. But I agree that it's a calculated risk. Is it more or less of a risk than RX meds for depression or anxiety for her? I personally believe it is less of one. YMMV, obviously.