Can you get a hold of the book & syllabus for both classes? Do you know of anyone in both classes who could let you see the book if the school doesn't. Do you know anyone who has skipped H. Biology and gone straight to AP Biology in YOUR SCHOOL? Biology is a huge topic and the AP covers a lot of material. As you can see from the variety of answers this depends on how the class is taught. And your child's learning style. Keep in mind that some schools the AMOUNT of work ramps up a lot is all the classes in high school. IMO the best way to answer this question is if you can see what the difference is between the two classes.