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    indigo #247439 08/02/20 06:41 AM
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    One Word Protects Your Brain from Diabetes and Dementia
    Donald Altman
    Psychology Today
    July 29, 2020

    “Sleep is critical to the function of the brain's waste removal system and this study shows that the deeper the sleep the better. These findings also add to the increasingly clear evidence that quality of sleep or sleep deprivation can predict the onset of Alzheimer's and dementia.”

    The glymphatic system only works when we sleep. Basically, it operates by compressing brain cells and pumping cerebral spinal fluid into the brain. This fluid cleanses out waste products, including the protein beta-amyloid, which is implicated in Alzheimer’s.
    Sleep may be important to aging gracefully, staying well, and maintaining a sharp mind.

    indigo #247441 08/02/20 08:46 AM
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    Yes it may. In addition, (this also has impacts on diabetes, heart disease, and other central obesity-related diseases) it helps regulate satiety/hunger signals.

    I should get more sleep!


    ...pronounced like the long vowel and first letter of the alphabet...
    indigo #247461 08/13/20 10:33 PM
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    Right under your nose: A more convenient way to diagnose Alzheimer's disease
    Certain proteins in nasal discharge can indicate the onset and progression of Alzheimer's, providing an avenue for early detection
    Date: August 11, 2020

    Summary:
    Scientists discover a new way to diagnose Alzheimer's disease by analyzing the levels of specific proteins in nasal discharge. This simple and inexpensive method could help in timely diagnosis of Alzheimer's disease, in order to start treatment as soon as possible, thus delaying disease progression.

    indigo #249306 11/01/21 06:12 AM
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    Hydra Vulgaris is utilized in studies on aging, due to its unique regeneration abilities.

    Links -
    1) https://biology.ucdavis.edu/research/model-organisms/hydra
    2) https://biology.ucdavis.edu/news/hydra-and-quest-understand-immortality (2018)

    indigo #249616 04/12/22 08:03 AM
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    Certain personality traits associated with cognitive functioning late in life
    American Psychological Association
    April 11, 2022
    Science Daily

    Originally Posted by article
    People who are organized, with high levels of self-discipline, may be less likely to develop mild cognitive impairment as they age, while people who are moody or emotionally unstable are more likely to experience cognitive decline late in life, according to new research.
    ...
    The research, published in the Journal of Personality and Social Psychology, focused on the role three of the so-called "Big Five" personality traits (conscientiousness, neuroticism and extraversion) play in cognitive functioning later in life.

    "Personality traits reflect relatively enduring patterns of thinking and behaving, which may cumulatively affect engagement in healthy and unhealthy behaviors and thought patterns across the lifespan," said lead author Tomiko Yoneda, PhD, of the University of Victoria.
    ...
    Future research is necessary on more diverse samples of older adults and should include the other two of the big five personality traits (agreeableness and openness) to be more generalizable and provide a broader understanding of the impact of personality traits on cognitive processes and mortality later in life, she said.
    I found this article to be well worth reading, fascinating, empowering, and hopeful.

    Your thoughts...?

    indigo #250004 09/09/22 05:41 AM
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    This study, and related article in easy-to-read layman's terms, point to the importance of diet to reduce the likelihood of Alzheimer's disease:

    study - https://www.frontiersin.org/articles/10.3389/fneur.2022.900048/full
    article - https://www.theepochtimes.com/regular-consumption-of-this-helps-keep-alzheimers-at-bay_4711696.html

    The article may be behind a paywall (if you know someone with a subscription, "friends read free").

    Brief excerpts:
    Originally Posted by article
    Alzheimer's patients' gut microbiomes differ tremendously from that of a healthy gut

    Lipopolysaccharide Is a Major Culprit of Alzheimer’s Disease

    The toxin is a variation of lipopolysaccharides (LPS)—BF-LPS. It is a neurotoxin secreted by the Bacteroides fragilis in the intestines and leaks from ruptured bowels, to enter the blood circulation system. It is capable of breaking through the blood-brain barrier (BBB) and entering the brain.

    Nuts Offset LPS Toxicity

    Bacteroides Love Saturated Fats
    The recommended dietary changes include:
    - reducing the intake of foods wth a high concentration of saturated fats,
    - increasing the intake of fiber including nuts such as almonds, hazelnuts, walnuts, macadamias, and pistachios.

    The article's explanations, graphics, and links to studies make it well worth reading and sharing.

    indigo #250039 10/08/22 05:57 AM
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    The Baltimore Longitudinal Study on Aging (BLSA) is ongoing and may be of interest: https://www.blsa.nih.gov/about

    Related articles from the National Institute on Aging (NIA):

    Normal Aging: https://www.nia.nih.gov/research/labs/blsa/what-normal-aging

    Healthy Aging: https://www.nia.nih.gov/health/what-do-we-know-about-healthy-aging

    Interestingly, the NIA also has a link to a recent article on a non-human species:
    "Aging deer downsize their home range and have fewer social connections" posted 10-06-2022 -
    https://www.nia.nih.gov/news/aging-deer-downsize-their-home-range-and-have-fewer-social-connections

    indigo #250112 12/01/22 02:33 PM
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    People in Their Nineties Share Tips for Longevity and Living Well
    link - https://www.brainandlife.org/articles/tips-for-longevity-living-well
    by Susan Fitzgerald
    Dec 2022 / Jan 2023
    Brain&Life

    The defining characteristic varies for each of the interviewees in this article, and include a preference for valuing qualities such as:
    - hardworking,
    - physical fitness,
    - staying connected,
    - determination.

    indigo #250477 09/07/23 03:00 AM
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    Neuroscience For Kids offers a monthly e-newsletter, packed with information on a wide range of topics from A to Z.
    The September 2023 e-newsletter included the following opportunity to become aware of recent research on Aging, as related to cognitive abilities:
    Older adults (aged 60-81 years old) who play digital puzzle games have similar memory and concentration abilities as younger adults (aged 18-30 years old)

    (Source: Cutting, J., et al., Higher working memory capacity and distraction-resistance associated with strategy (not action) game playing in younger adults, but puzzle game playing in older adults. Heliyon, 2023; 9 (8): e19098 DOI: 10.1016/j.heliyon.2023.e19098).
    Link to referenced study - https://www.cell.com/heliyon/fulltext/S2405-8440(23)06306-5
    - - Authors: Joe Cutting, Bethany Copeland, Fiona McNab
    - - Open Access
    - - Published: August 11, 2023
    - - DOI: https://doi.org/10.1016/j.heliyon.2023.e19098

    Link to Neuroscience For Kids - https://faculty.washington.edu/chudler/neurok.html
    Link to Neuroscience For Kids, about - https://faculty.washington.edu/chudler/whowe.html
    Link to Neuroscience For Kids, e-newsletter signup - https://faculty.washington.edu/chudler/newslet.html

    indigo #250529 10/05/23 09:11 PM
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